Dr. Alessia Ruggieri

Department of Infectious Diseases, Molecular Virology Heidelberg University
69120 Heidelberg, Germany

Phone: +49 6221-56 7761
Fax:      +49 6221-56 4570
Email:   alessia.ruggieri@med.uni-heidelberg.de

FIELDS OF INTEREST

Molecular virology, dynamics of cellular stress and immune responses to RNA virus infection, quantitative live-cell imaging

2013–present Junior Group Leader in the Dpt of Infectious Diseases, Molecular Virology,Heidelberg University
2008–2013 Postdoctoral in the lab of Ralf Bartenschlager, University of Heidelberg
2004–2008 Postdoctoral at the Institute of Human Genetics, University of Saarland
1999–2003 Ph.D. Virology, Ecole Normale Supérieur de Lyon, France
1998–1999 Diploma thesis, University of Lyon, France
1995–1998 Studies in Cellular and Molecular Biology Metz and Lyon, France

Ruggieri A, Dazert E, Metz P, Hofmann S, Bergeest JP, Mazur J, Bankhead P, Hiet MS, Kallis S, Alvisi G, Samuel CE, Lohmann V, Kaderali L, Rohr K, Frese M, Stoecklin G, Bartenschlager R. Dynamic oscillation of translation and stress granule formation mark the cellular response to virus infection. Cell Host Microbe 2012; 12(1):71-85

Bauhofer O, Ruggieri A, Schmid B, Schirmacher P, Bartenschlager R. Persistence of HCV in quiescent hepatic cells under conditions of an interferon-induced antiviral response. Gastroenterology 2012; 143(2):429-438

Metz P, Dazert E, Ruggieri A, Mazur J, Kaderali L, Kaul A, Zeuge U, Trippler M, Lohmann V, Binder M, Frese M, Bartenschlager R. Identification of type I and type II interferon-induced effectors controlling hepatitis C virus replication. Hepatology 2012; 56(6):2082-93.

Ruggieri A, Maldener E, Sauter M, Mueller-Lantzsch N, Meese E, Fackler OT, Mayer J. Human endogenous retrovirus HERV-K(HML-2) encodes a stable signal peptide with biological properties distinct from Rec. Retrovirology 2009; (16):6-17

Ruggieri A*, Cheynet V*, Oriol G, Blond JL, Boson B, Vachot L, Verrier B, Cosset FL, Mallet F. Synthesis, assembly, and processing of the Env ERVWE1/syncytin human endogenous retroviral envelope. J Virol. 2005; 79(9):5585-93

*equal contributions

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