PD Dr. E. Ada Cavalcanti-Adam

Institute of Physical Chemistry (PCI), Department of Biophysical Chemistry,
Heidelberg University and Max-Planck-Institute for Intelligent Systems Stuttgart
69120 Heidelberg, Germany

Phone: +49 6221-54 5064
Fax:      +49 6221-54 4950
Email:   Ada.Cavalcanti-Adam@urz.uni-heidelberg.de

FIELDS OF INTEREST

Cell biology, cell adhesion and motility, cell-extracellular matrix interactions, integrin signaling and crosstalk, biophysics, biomaterials.

AWARDS & HONORS

2008-2010 Christiane Nüsslein-Volhard Stiftung and UNESCO-L’Orèal Prize “for women in science”
2004-2006 Marie Curie European Fellowship FP-6 Mobility from European Commission
2003-2004 Frauenförderung Stipendium, faculty of Medicine, University of Heidelberg
2001 Kress Research Award
1997 Italian National Scholarship
1996 Award “Lina Marinaccio” for biomedical disciplines

CURRENTLY FUNDED PROJECTS

DFG, SFB/TRR79 “materials for tissue regeneration of systemically diseased bone”:

  • TP M6 “structuring and functionalization of surfaces for the control of bone cell adhesion and behavior”
  • TP B5 “Modification of cell-cell and cell-matrix communication in bone tissues through the use of novel materials”

2013-present Head of Central Scientific Facility “Biomaterials”- Molecular Biology section, Max Planck Institute for Intelligent Systems
2008-present Group leader Heidelberg University and Max Planck Institute for Intelligent Systems, Stuttgart
2005-2008 PostDoc, Max-Planck-Institute for Metals Research Stuttgart
2005 PhD, faculty of Biology, Heidelberg University
2002 – present Adjunct Assistant Professor, Dept. Orthodontics, University of Pennsylvania
2001 MSc, Master of Science Biology, University of Pennsylvania (USA)
2001-2002 PostDoc, Department of Bioengineering, University of Pennsylvania
2000 Specialty certification in Orthodontics and Dentofacial Orthopaedics, University of Pennsylvania
1998-2000 Postgraduate resident fellow, Dept. Orthodontics, School of Dental Medicine, University of Pennsylvania
1995-1998 Clinical general dentistry
1995 DMD, Doctor Medical Dentistry, University of Bari (Italy)

Rechenmacher F, Neubauer S, Polleux J, Mas-Moruno C, De Simone M, Cavalcanti-Adam EA, Spatz JP, Fässler R, Kessler H, Functionalizing avb3 or a5b1- selective integrin antagonists for surface coating: a new tool to discriminate integrin subtypes in vitro. Angew Chemie Intl Ed, 2013; 52(5), 1572-75

Pohl TL, Boergermann JH, Schwaerzer GK, Knaus P, Cavalcanti-Adam EA, Covalently immobilized bone morphogenetic protein 2 induces signaling responses for osteoblast differentiation. Acta Biomaterialia, 2012; 8(2), 772-80

Cavalcanti-Adam EA, Volberg T, Micoulet A, Kessler H, Geiger B, Spatz JP, Cell spreading and focal adhesion dynamics are regulated by spacing of integrin ligands. Biophys J. 2007; 92(8), 2964-74

Arnold M, Cavalcanti-Adam EA, Glass R, Blümmel Jl, Eck W, Kantlehner M, Kessler H, Spatz JP, Activation of integrin function by nanopatterned adhesive interfaces. Chemphyschem, 2004; 5(3), 383-88

Cavalcanti-Adam EA, Shapiro IM, Macarak EJ, Composto RJ, Adams CS, Dynamic equibiaxial strain causes intracellular changes in osteoblasts cultured on RGD-engineered surfaces. J Bone Miner Research, 2002; 17(12), 2130-41

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