Barbara_Mueller

apl. Prof. Dr. Barbara Müller

Department of Infectious Diseases, Virology Heidelberg University
69120 Heidelberg, Germany

Phone: +49 6221-56 1325
Fax:      +49 6221-56 5003
Email:   barbara.mueller@med.uni-heidelberg.de

FIELDS OF INTEREST

Biology of human immunodeficiency virus. Focus of current work: live-cell imaging of HIV-1 cell interactions; analysis of dynamics of HIV cell entry and HIV particle formation; HIV assembly and maturation; quantitative analysis of HIV replication steps

CURRENTLY FUNDED PROJECTS

Project 6 in SFB1129 (1 Postdoc); DFG Grant MU885/5-1 (2 PhD students); EcTop programme of the CellNetworks Cluster of Excellence, EXC81 (1 Masters Student)

AWARDS & HONORS

1992-1997 Postdoctoral Fellowship (AIDS-Stipendienprogramm BMBF)

 

2000–present Group leader at the Department of Infectious Diseases, Virology, Heidelberg University
2015 apl. Prof. at the Heidelberg University
2004 Habilitation in Experimental Virology (Heidelberg University)
1995–2000 Postdoctoral fellow/ research associate, Heinrich-Pette-Institute, Hamburg, Department of Cell Biology and Virology
1995 Postdoctoral fellow , German Cancer Research Center Heidelberg
1992–1995
1991–1992
Postdoctoral fellow, Fox Chase Cancer Center Philadelphia PA, USA
Postdoctoral associate, Max-Planck-Institute for Medical Research Heidelberg
1991 PhD (Dr. rer. nat.), University of Heidelberg
1988–1991 PhD thesis (Max-Planck-Institute for Medical Research Heidelberg, lab of Prof. R.S.Goody)
1987 Diploma (University of Heidelberg)
1981–1986 Study of Biology, Technical University Darmstadt and University of Heidelberg

5 SELECTED PUBLICATIONS  (**:corresponding author)

Chojnacki,J. and Müller, B.** Investigation of HIV-1 assembly and release using modern fluorescence imaging techniques. Review. Traffic 2013 14, 15-24.

de Marco, A., Heuser, A.M., Glass, B., Kräusslich, H.G., Müller, B.**, and Briggs, J.A.** . The role of the SP2 domain and its proteolytic cleavage in HIV-1 structural maturation and infectivity. Journal of virology 2012 86, 13708-16

Bozek K, Eckhardt M, Sierra S, Anders M, Kaiser R, Kräusslich HG, Müller B**, Lengauer T**: An expanded model of HIV cell entry phenotype based on multi-parameter single-cell data. Retrovirology 2012, 9:60

Baumgärtel V, Ivanchenko S, Dupont A, Sergeev M, Wiseman PW, Kräusslich HG, Bräuchle C, Müller B**, Lamb DC**: Live-cell visualization of dynamics of HIV budding site interactions with an ESCRT component. Nat Cell Biol 2011, 13:469-474

Ivanchenko S, Godinez WJ, Lampe M, Kräusslich HG, Eils R, Rohr K, Bräuchle C, Müller B**, Lamb DC**: Dynamics of HIV-1 assembly and release. PLoS Pathog 2009, 5:e1000652

Click here for a complete list of scientific publications.