Projects of SFB 1129

27 Projects and 35 research profiles from different disciplines.

An integrative perspective on the mutual interplay of pathogen and host factors determining the outcome of an infection for individual events in systems of different complexity and at high spatial and temporal resolution.


Project 1 – Fischknecht und Spatz
Deciphering receptor-ligand interplay during rapid motility of Plasmodium sporozoites

Project 2 – Müller und Grimm
Role of intra- and extra-cellular host miRNAs as regulators of Plasmodium liver stages
(10/2014 – 06/2018)

Project 3 – Lanzer und Tanaka
Protection of malaria by haemoglobin S and C: A quantitative understanding of the cytoadhesion behavior

Project 4 – Schwarz und Lanzer
Modeling the adhesion of malaria-infected red blood cells

Project 5 – Kräusslich
HIV-1 capture and spread at nanoscopic resolution

Project 6 – Müller
Dynamics of events in HIV-1 replication

Project 7 – Lemke
Pathogen passage through the Nuclear Pore Complex
(10/2014 – 06/2022)

Project 8 – Fackler
HIV-1 spread in complex cell systems

Project 9 – Briggs
The assembly and spread of influenza Virus
(10/2014 – 06/2018)

Project 10 – Brügger und Kräusslich
Membrane lipids and proteins in influenza replication and spread
(10/2014 – 06/2022)

Project 11 – Bartenschlager und Höfner
Spatial and temporal coordination of RNA translation,
replication and assembly in a membranous plus-strand RNA virus replication factory

Project 13 – Ruggieri
Impact of virus-induced oscillating stress response on host cell homeostasis

Project 14 – Boulant
Visualizing enteric Virus infection of intestinal Epithelium: From touchdown to antiviral innate immune response
(10/2014 – 06/2022)

Project 15 – Calvacanti-Adam und Grimm
Nanoscale characterization of integrin-virus interactions

Project 16 – Urban und Grimm
Visualization of Hepatitis B Virus entry and spread
(10/2014 – 06/2022)

Project 17 – Dao Thi
Hepatitis E virus trafficking in polarized human pluripotent stem cell-derived hepatocyte-like systems

Project 18 – Ganter
Deciphering the regulation of Plasmodium falciparum replication

Project 19 – Schlanda
Structural analysis of influenza protein-membrane interactions during entry

Project 20 – Lusic und Beck
Nuclear pore complex and genome organiszation as determinants of HIV-1 integration and transcription

Project 21 – Briggs
The role of matrix maturation in HIV-1 infection and spread

Project 22 – Selhuber-Unkel und Fischknecht
The role of mechanosensing and antibodies for interactions of Plasmodium sporozoites with neutrophils in 3D environments

Project 23 – Ingham
How insecticides impact malaria parasite infectivity

Project 24 – Mücksch
Host cell determinants for establishment and reversal of HIV-1 latency


Project Z2 – Funaya und Schwarz
Correlative light and electron microscopy

Project Z3 – Johnsson
Chemical biology tools for infectious diseases research
(10/2014 – 06/2022)

Project Z4 – Hamprecht und Rohr
Advanced Tracking and Image Analysis

Mercator fellow
Mercator fellow associated with the SFB1129