Dr. Petr Chlanda

Department of Infectious Diseases, Virology
Heidelberg University Schaller Research Group
69120 Heidelberg, Germany

Phone: +49 6221-54 51231
Fax:      +49 6221-56 5005
Email:   petr.chlanda@bioquant.uni-heidelberg.de

FIELDS OF INTEREST
Structural cell biology and virology, influenza A virus, Ebola virus, membrane remodeling and role of lipids in viral infection, membrane fusion, cryo-electron tomography, correlative light and electron microscopy methods

  

CURRENTLY FUNDED PROJECTS
Chica and Heinz Schaller Foundation Group leader (2017-2022)

 

09/2017 – present

Schaller Research Group Leader, Center for Infectious Diseases, Heidelberg Univeristy

2011 – 2017

PostDoc, Section on Integrative Biophysics, National Institute of Child Health and Human Development, National Institute of Health, Bethesda, USA

2010 – 2011 PostDoc, Structural and Computational Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany
2006 – 2009 PhD in Virology (Heidelberg University)
2000 – 2006 M.S. in Biochemistry (Charles University, Prague)

2018 – present Member of Cryo-Electron Microscopy Steering Committee, Heidelberg University

1. Chlanda P, Mekhedov E, Waters H, Sodt A, Schwartz C, Nair V, Blank PS, Zimmerberg J. 2017. Palmitoylation contributes to membrane curvature in Influenza A virus assembly and hemagglutinin-mediated membrane fusion. J. Virol. pii: JVI.00947-17.
2. Chlanda P. 2017. Influenza Hemagglutinin and M2 ion channel priming by trypsin: Killing two birds with one stone. Virology. 509:131-132.
3. *Quemin ERJ, *Chlanda P, Sachse M, Forterre P, Prangishvili D, Krupovic M. 2016. Eukaryoticlike virus budding in Archaea. MBio. 7(5):e01439-16 (*equal contribution)
4. Chlanda P, Mekhedov E, Waters H, Schwartz CL, Fischer ER, Ryham RR, Cohen FS, Blank PS, Zimmerberg J. 2016. The hemifusion structure induced by Influenza virus hemagglutinin is determined by physical properties of the target membranes. Nat Microbiol. 1(6):16050.
5. Chlanda P, Zimmerberg J. 2016. Protein-lipid interactions critical to replication of the influenza A virus during infection. FEBS Lett. 590(13):1940-1954.
6. Chlanda P, Riches J, Oberwinkler H, Schraidt O, Kräusslich HG, Briggs JAG. 2015. Structural analysis of the contributions of individual proteins to influenza assembly and morphology. J Virol. 89(17):8957-66.
7. Chlanda P, Sachse M. 2014. Cryo-Electron Microscopy of Vitreous Sections. Methods Mol Biol. 1117:193-214.
8. Chlanda P, Carbajal MA, Cyrklaff M, Griffiths G, Krijnse-Locker J. Membrane rupture generates single open membrane sheets during vaccinia virus assembly. 2009. Cell Host Microbe. 6(1):81-90.