Prof. Dr. Kai Johnsson

Department of Chemical Biology
Max-Planck-Institute for Medical Research
69120 Heidelberg

Phone: 06221-486-400
Email: Kai.Johnsson@mpimf-heidelberg.mpg.de

FIELDS OF INTEREST

CURRENTLY FUNDED PROJECTS

AWARDS & HONORS

2016 Karl Heinz Beckurts-Preis
2015 AbbVie Lecture, UC Berkeley
2013 Elected Member of EMBO
2012-2013 Novartis Lectureship Award
2011 Amgen Lecture, UC Berkeley
2003 Prix APLE for the invention of the year 2003 of EPFL Lausanne

2010-present Director, Max-Planck-Institute for Medical Research, Department of Chemical Biology, Heidelberg, Germany
2009-2017 Full Professor, Institute of Chemical Sciences and Engineering, EPFL Lausanne, Switzerland
2005-2009 Associate Professor, Institute of Chemical Sciences and Engineering, EPFL Lausanne
1999-2005 Assistant Professor, Institute of Chemical Sciences and Engineering, EPFL Lausanne
1996-1999 Independent Researcher, Ruhr-University Bochum, Germany
1993-1996 Postdoctoral fellow, Department of Chemistry, UC Berkeley, USA

2015-present Scientific Advisory Commission of EMBL
2014-present Scientific Advisory Board, Quartet Medicines, Boston, USA
2012-present Editorial Advisory Board of Science
2012-present Member of the school-wide tenure committee of EPFL
2010-present Co-Director of the Swiss-wide research program NCCR Chemical Biology
2009-present Member of the steering committee of Institute of Chemical Sciences, EPFL
2006-present Editorial Board  of Chemistry&Biology, ChemBioChem, Chemical Society Reviews
2005-present Associate Editor of ACS Chemical Biology
2003-2010 Board of Directors, Covalys Biosciences, Switzerland

1. Lukinavicius G, Reymond L, Umezawa K, Sallin O, D’Este E, Gottfert F, Ta H, Hell SW, Urano Y, Johnsson K. 2016. Fluorogenic probes for multicolor imaging in living cells. J Am Chem Soc. 138 (30):9365-9368
2. Xue L, Prifti E, Johnsson K. 2016. A general strategy for the semisynthesis of ratiometric fluorescent sensor proteins with increased dynamic range. J Am Chem Soc. 138 (16):5258-5261
3. Lukinavicius G, Reymond L, D’Este E, Masharina A, Gottfert F, Ta H, Guther A, Fournier M, Rizzo S, Waldmann H, Blaukopf C, Sommer C, Gerlich DW, Arndt HD, Hell SW, Johnsson K. 2014. Fluorogenic probes for live-cell imaging of the cytoskeleton. Nature Methods. 11 (7):731-733
4. Griss R, Schena A, Reymond L, Patiny L, Werner D, Tinberg CE, Baker D, Johnsson K. 2014. Bioluminescent sensor proteins for point-of-care therapeutic drug monitoring. Nat Chem Biol. 10(7):598-603
5. Haruki H, Pedersen MG, Gorska KI, Pojer F, Johnsson K. 2013. Tetrahydrobiopterin biosynthesis as an off-target of sulfa drugs. Science. 340 (6135):987-991
6. Lukinavicius G, Umezawa K, Olivier N, Honigmann A, Yang G, Plass T, Mueller V, Reymond L, Correa IR Jr, Luo ZG, Schultz C, Lemke EA, Heppenstall P, Eggeling C, Manley S, Johnsson K. 2013. A near-infrared fluorophore for live-cell super-resolution microscopy of cellular proteins. Nature chemistry. 5 (2):132-139
7. Gautier A, Juillerat A, Heinis C, Correa IR, Kindermann M, Beaufils F, Johnsson K. 2008. An engineered protein tag for multiprotein labeling in living cells. Chem Biol. 15 (2):128-136
8. Chidley C, Haruki H, Pedersen MG, Muller E, Johnsson K. 2011. A yeast-based screen reveals that sulfasalazine inhibits tetrahydrobiopterin biosynthesis. Nat Chem Biol. 7 (6): 375-383
9. Keppler A, Pick H, Arrivoli C, Vogel H, Johnsson K. 2004. Labeling of fusion proteins with synthetic fluorophores in live cells. PNAS. 101 (27):9955-9959
10. Keppler A, Gendreizig S, Gronemeyer T, Pick H, Vogel H, Johnsson K. 2003. A general method for the covalent labeling of fusion proteins with small molecules in vivo. Nat Biotechnol. 21 (1):86-89