International Symposium 2017


International Symposium 2017 of SFB 1129 on
Integrative Analysis of Pathogen Replication and Spread
July 20 – 22, 2017
 at Bioquant-Center, Heidelberg

The symposium will showcase the diversity of modern approaches to study pathogens and how they interact with their host cells and organisms. Speakers and posters focus on HIV, influenza, hepatitis viruses and Plasmodium. The featured methodologies reach from single molecule and biophysical analysis to in vivo imaging and genome wide approaches.

Prof. Dr. Hans-Georg Kräusslich, Center for Infectious Diseases, Virology, INF 324, Heidelberg
Prof. Dr. Oliver Fackler, Center for Infectious Diseases, Integrative Virology, INF 324, Heidelberg
Prof. Dr. Friedrich Frischknecht, Center for Infectious Diseases, Integrative Parasitology, INF 345, Heidelberg

Confirmed Speakers

  • Paul Ahlquist, Madison, USA
  • Monsef Benkirane, Montpellier, France
  • Oliver Billker, Cambridge, UK
  • Pamela Bjorkman, Pasadena, USA
  • Viet Loan Dao Thi, New York, USA
  • Luca G. Guidotti, Milan, Italy
  • Matthias Gunzer, Essen, Germany
  • Michael Hagan, Waltham, USA
  • Andreas Herrmann, Berlin, Germany
  • Volker Heussler, Bern, Switzerland
  • Chwee Teck Lim, Singapore
  • Marina Lusic, Heidelberg, Germany
  • Thorsten Mempel, Charlestown, USA


Thursday, July 20 2017

10.00-12.00 a.m. Registration and poster setup
12.00-01.00 p.m.  Welcome buffet
1.00 Opening and welcome
Hans-Georg Kräusslich, Heidelberg
1.05-1.40 New structure/function insights into viral RNA replication compartments
Paul Ahlquist, Madison
1.40-2.15 Hepatitis C virus –host cell interaction: Making the invisible visible
Ralf Bartenschlager, Heidelberg
2.15-2.50 Pan-genotype HEV replication in stem cell-derived hepatocellular systems
Viet Loan Dao Thi, New York
2.50-3.20 Coffee break
3.20-3.55 Stress management: Modulation of the host stress response by RNA viruses
Alessia Ruggieri, Heidelberg
3.55-4.30 Mechanobiological insights into the pathophysiology of malaria
Chwee Teck Lim, Singapore
4.30-6.00 Poster session in the BIOQUANT foyer
6.00 Light dinner, Bioquant Foyer

Friday, July 21 2017

9.00-9.35 Paving the way towards elimination of HIV persistent CD4 T cells in vivo
Monsef Benkirane, Montpellier
9.35-10.10 Nuclear landscape of HIV-1 integration and transcription
Marina Lusic, Heidelberg
10.10-10.45 Imaging molecular events in HIV-1 post entry
Barbara Müller, Heidelberg
10.45-11.20 Coffee break
11.20-11.55 A molecular arms race: HIV versus the immune system
Pamela Björkman, Pasadena
11.55-12.30 Applying advanced imaging to quantify the outcome of infection defense and autoimmunity on three functional scales
Matthias Gunzer, Essen
12.30-1.30 Lunch break
1.30-2.05 Cellular and viral dynamics in mucosal and lymphoid tissues during HIV transmission
Thorsten Mempel, Charlestown
2.05-2.40 3D environments shape modes of HIV-1 spread
Oliver T. Fackler, Heidelberg
2.40-3.15 Advanced imaging to study HBV pathogenesis in animal models
Luca G. Guidotti, Milan
3.15-3.45 Coffee break
3.45-4.20 Cytosolic immune responses of host hepatocytes against Plasmodium infection and parasite escape mechanism
Volker Heussler, Bern
4.20-4.55 Deciphering the assembly of multi-segment genome complexes in Influenza a Virus
Andreas Herrmann, Berlin
5.00 Visit of the CIID (INF 344) for all interested participants
5.45 “Kamingespräch” of students and postdocs with Andreas Herrmann (Marsilius Kolleg INF 130)
7.00 Speaker’s Dinner

Saturday, July 22 2017

9.00-9.35 Tools to study pathogen passage through the nuclear pore complex
Edward A. Lemke, Heidelberg
9.35-10.10 Simulating the assembly of viruses and bacterial microcompartments
Michael Hagan, Waltham
10.10-10.45 The role of cell adhesion in the malaria life cycle
Ulrich Schwarz, Heidelberg
10.45-11.20 Coffee break
11.20-11.55 Insights into parasite genome evolution and life cycle regulation from global genetic screens in Plasmodium
Oliver Bilker, Cambridge
11.55-12.30 New views of virus structure and assembly from cryo-EM
John A.G. Briggs, Cambridge
12.30 Closure of the meeting
From 2.00 p.m. Summer party of the Department of Infectious Diseases:
Celebrating the125th anniversary of the Hygieneinstitut / Zentrum für Infektiologie


Registration is now closed.


For questions please contact:

Jutta Stephan
Department of Infectious Diseases, Virology
Im Neuenheimer Feld 324, 69120 Heidelberg
phone: +49 (0)6221 56-6269

Venue and Accommodation

Venue: All sessions of this symposium will take place at

Im Neuenheimer Feld 267
69120 Heidelberg

How to get to Bioquant-Center:

  • Coming from the motorway (A 656): Turn left towards “Chirurgie” at the end of the Autobahn. Having crossed the Neckar on Ernst-Waltz-Brücke follow Berliner Straße. At the 2nd traffic light (“Shell” gas station & “Bunsengymnasium”) turn left towards Neuenheimer Feld (Bioquant, building 267).

Due to the limited number of parking lots in the Neuenheimer Feld, it is recommended to use public transport.

  • From main railway station (Hauptbahnhof): Take either the tram number 24 (direction Handschuhsheim) or the number 21 (direction Technologiepark) and get off at the “Bunsengymnasium” stop.
  • From Heidelberg downtown (Bismarckplatz): Take the bus number 31 towards “Neuenheim, Chirurgische Klinik” and get off at the “Bunsengymnasium” bus stop.
  • From Frankfurt/Main airport there is a train connection to Heidelberg via Mannheim main station (ca. 1h travel time).
    For information about transport by airport shuttle click here


Please make your 
own travel and hotel arrangements.
Heidelberg offers a wide range of hotels in different prize categories. For a full list of hotels, please check: or Heidelberg Tourist Info.

This symposium is funded by