Dr. A. Ruggieri

(*equal corresponding author)

Talemi SR, Bartenschlager M, Schmid B, Ruggieri A*, Bartenschlager R*, Höfer T*. 2021. Dengue virus is sensitive to inhibition prior to productive replication. Cell Rep 37(2):109801

Cortese M, Lee J-Y, Cerikan B, Neufeldt CJ, Oorschot VMJ, Köhrer S, Hennies J, Schieber NL, Ronchi P, Mizzon G, Romero Brey I, Santarella-Mellwig R, Schorb M, Boermel M, Mocaer K, Beckwith MS, Templin RM, Gross V, Frankish J, Horvat NK, Laketa V, Stanifer M, Boulant S, Ruggieri A, Chatel-Chaix L, Schwab Y, Bartenschlager R. 2020. Integrative imaging reveals SARS-CoV-2 induced reshaping of subcellular morphologies. Cell Host Microbe 28(6):853-866.e5

Haneke K, Schott J, Lindner D, Hollensen AK, Damgaard CK, Mongis C, Knop M, Palm W, Ruggieri A, Stoecklin G (2020). CDK1 couples proliferation with protein synthesis. J Cell Biol. 219(3): e201906147.

Brocard M, Iadevaia V, Klein P, Hall B, Lewis G, Lu J, Burke J, Willcocks M, Parker R, Goodfellow IG, Ruggieri A, Locker N (2020). Norovirus infection results in eIF2α-independent host translation shut-off and remodels the G3BP1 interactome evading stress granule formation. PLoS Pathog. 16(1):e1008250.

Lee J-Y, Cortese M, Haselmann U, Tabata K, Romero-Brey I, Funaya C, Rohr K, Qiang Y, Ritter C, Schwab Y, Schieber N, Bartenschlager M, Kallis S, Ruggieri A, Bartenschlager R (2019). Spatio-temporal coupling of the hepatitis C virus replication cycle by creation of a li-pid droplet proximal membranous replication compartment. Cell Rep. 27(12):3602-3617.e5.

Roth H, Magg V, Uch F, Mutz P, Klein P, Haneke K, Lohmann V, Bartenschlager R, Fackler OT, Locker N, Stoecklin G, Ruggieri A (2017). Flavivirus infection uncouples translation suppression from cellular stress responses. mBio. 8:e02150-16

Cortese M, Goellner S, Acosta EG, Neufeldt CJ, Oleksiuk O, Lampe M, Haselmann U, Fu-naya C, Schieber N, Ronchi P, Schorb M, Pruunsild P, Schwab Y, Chatel-Chaix L, Ruggieri A, Bartenschlager R. (2017). Ultrastructural characterization of Zika virus replication facto-ries. Cell Reports. 18(9):2113–2123

Chatel-Chaix L, Cortese M, Romero-Brey I, Bender S, Fischl W, Scaturro P, Fischer B, Ruggieri A, Bartenschlager R (2016). Dengue virus modulates mitochondrial morphodynam-ics through the inhibition of DRP-1 for the benefit of viral replication. Cell Host Microbe. 20(3):342-56

Hiet MS, Bauhofer O, Zayas M, Roth H, Tanaka Y, Schirmacher P, Willemsen J, Grünvogel O, Bender S, Binder M, Lohmann V, Lotteau V, Ruggieri A*, Bartenschlager R* (2015). Control of temporal activation of hepatitis C virus-induced interferon response by domain 2 of nonstructural protein 5A. J Hepatol. 63(4):829-837

Ruggieri A, Dazert E, Metz P, Hofmann S, Bergeest JP, Mazur J, Bankhead P, Hiet MS, Kal-lis S, Alvisi G, Samuel CE, Lohmann V, Kaderali L, Rohr K, Frese M, Stoecklin G, Bartenschlager R (2012). Dynamic oscillation of translation and stress granule formation mark the cellular response to virus infection. Cell Host Microbe. 12(1):71-85

Click here for further publications.