Dr. Martin Beck

Max Planck Institute of Biophysics
Max-von-Laue-Straße 3
60438 Frankfurt am Main
Germany

Phone: +49 69 6303 3501
E-Mail

FIELDS OF INTEREST
nucleocytoplasmic transport, integrated structural biology, systems biology and biogenesis of protein complexes

  

AWARDS & HONORS

2022      ERC Advanced Grant
2018      ERC Investigator (Consolidator Grant)
2013      ERC Investigator (Starting Grant)
2012      Walther Flemming Medal
2007      Marie Curie Intra European Fellowship
2006      Long Term Fellowship of the European Molecular Biology Organization
2005      Junior Research Award of the Max Planck Institute of Biochemistry

2019-present Director and Scientific Member, Max-Planck Institute of Biophysics, Frankfurt
2017-2019 Senior Scientist, EMBL Heidelberg
2010-2020 Group Leader, EMBL Heidelberg
2006-2009 Postdoc, ETH Zurich
2002-2006 PhD student, Max Planck Institute of Biochemistry, Martinsried
10/2001 – 3/2002 Research Intern, Rockefeller Univeristy, New York
2016-2020 Elected member of the review board of the German Research Foundation, study section Biochemistry
2015 Vice chair for FET-OPEN call of the European Commission
2012 – present present Editorial board member of Molecular Cellular Proteomics

Zimmerli CE, Allegretti M, Rantos V, Goetz SK, Obarska-Kosinska A, Zagoriy I, Halavatyi A, Hummer G, Mahamid J, Kosinski J, Beck, M. 2021. Nuclear pores dilate and constrict in cellulo. Science 374, eabd9776

Zila, V., Margiotta, E., Turoňová, B., Müller, T.G., Zimmerli, C.E., Mattei, S., Allegretti, M., Börner, K., Rada, J., Müller, B., Lusic, M., Kräusslich, H.G.*, Beck, M.* (2021). Cone-shaped HIV-1 capsids are transported through intact nuclear pores. Cell 184, 1-15.

Allegretti, M., Zimmerli, C.E., Rantos, V., Wilfling, F., Ronchi, P., Fung, H.K.H., Lee, CW., Hagen, W., Turoňová, B., Karius, K., Börmel, M., Zhang, X., Müller, C., Schwab, Y., Mahamid, J., Pfander, B., Kosinski, J., Beck, M.* (2020). In cell architecture of the nuclear pore complex and snapshots of its turnover. Nature 586, 796-800.

Turoňová, B., Sikora, M., Schürmann, C., Hagen, W.J.H., Welsch, S., Blanc, F.E.C., von Bülow, S., Gecht, M., Bagola, K., Hörner, C., v Zandbergen, G., Landry, J., Doimo de Azevedo, N.T., Mosalaganti, S., Schwarz, A., Covino, R., Mühlebach, M.D., Hummer, G.*, Krijnse Locker, J.*, Beck, M*. (2020). In situ structural analysis of SARS-CoV-2 spike reveals flexibility mediated by three hinges. Science 370, 203-208.

Hampoelz, B., Schwarz, A., Ronchi, P., Bragulat-Teixidor, H., Tischer, C., Gaspar, I., Ephrussi, A., Schwab, Y. and Beck, M.* (2019). Nuclear Pores Assemble from Nucleoporin Condensates During Oogenesis. Cell 179(3), 671-686.

Hampoelz, B., Mackmull, M.-T., Machado, P., Ronchi, P., Bui, K.H., Schieber, N., Santarella-Mellwig, R. Necakov, A., Andres-Pons, A., Philippe, J.M., Lecuit, T., Schwab, Y. and Beck, M.* (2016). Pre-assembled nuclear pores insert into the nuclear envelope during early development. Cell 166(3), 664-678.

Kosinski, J., Mosalaganti, S., von Appen, A., Teimer, R., DiGuilio, L., Wan, W., Bui, H.K., Hagen W.J.H., Briggs, J.A.G., Glavy, J.S., Hurt, E. and Beck, M.* (2016). Molecular architecture of the inner ring scaffold of the human nuclear pore complex. Science 352, 363-5.

von Appen, A., Kosinski, J., Sparks, L., Ori, A., DiGuilio, A.L., Vollmer, B., Mackmull, M.-T., Banterle, N., Parca, L., Kastritis, P., Buczak, K., Mosalaganti, S., Hagen, W., Andres-Pons, A., Lemke, E.A., Bork, P., Antonin, W., Glavy, J.S., Bui, H.K.* and Beck, M.* (2015). In situ structural analysis of the human nuclear pore complex. Nature 526, 140–143.

Bui, H.K., von Appen, A., DiGuilio, A.L., Ori, A., Sparks, L., Mackmull, M.-T., Bock, T., Hagen, W., Andres-Pons, A., Glavy, J.S.* and Beck, M.* (2013). Integrated structural analysis of the human nuclear pore complex scaffold. Cell 155(6), 1233-43.

Ori A, Banterle N, Iskar M, Andrés-Pons A, Escher C, Bui HK, Sparks L, Solis-Mezarino VM, Rinner O, Bork P, Lemke EA, Beck M. 2013. Cell type-specific nuclear pores: A case in point for context-dependent stoichiometry of molecular machines. Molecular Systems Biology 9, 648

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