Dr. Martin Beck
Max Planck Institute of Biophysics
Max-von-Laue-Straße 3
60438 Frankfurt am Main
Germany
Phone: +49 69 6303 3501
E-Mail
FIELDS OF INTEREST
nucleocytoplasmic transport, integrated structural biology, systems biology and biogenesis of protein complexes
AWARDS & HONORS
2022 ERC Advanced Grant
2018 ERC Investigator (Consolidator Grant)
2013 ERC Investigator (Starting Grant)
2012 Walther Flemming Medal
2007 Marie Curie Intra European Fellowship
2006 Long Term Fellowship of the European Molecular Biology Organization
2005 Junior Research Award of the Max Planck Institute of Biochemistry
| 2019-present | Director and Scientific Member, Max-Planck Institute of Biophysics, Frankfurt |
| 2017-2019 | Senior Scientist, EMBL Heidelberg |
| 2010-2020 | Group Leader, EMBL Heidelberg |
| 2006-2009 | Postdoc, ETH Zurich |
| 2002-2006 | PhD student, Max Planck Institute of Biochemistry, Martinsried |
| 10/2001 – 3/2002 | Research Intern, Rockefeller Univeristy, New York |
| 2016-2020 | Elected member of the review board of the German Research Foundation, study section Biochemistry |
| 2015 | Vice chair for FET-OPEN call of the European Commission |
| 2012 – present | present Editorial board member of Molecular Cellular Proteomics |
Zimmerli CE, Allegretti M, Rantos V, Goetz SK, Obarska-Kosinska A, Zagoriy I, Halavatyi A, Hummer G, Mahamid J, Kosinski J, Beck, M. 2021. Nuclear pores dilate and constrict in cellulo. Science 374, eabd9776
Zila, V., Margiotta, E., Turoňová, B., Müller, T.G., Zimmerli, C.E., Mattei, S., Allegretti, M., Börner, K., Rada, J., Müller, B., Lusic, M., Kräusslich, H.G.*, Beck, M.* (2021). Cone-shaped HIV-1 capsids are transported through intact nuclear pores. Cell 184, 1-15.
Allegretti, M., Zimmerli, C.E., Rantos, V., Wilfling, F., Ronchi, P., Fung, H.K.H., Lee, CW., Hagen, W., Turoňová, B., Karius, K., Börmel, M., Zhang, X., Müller, C., Schwab, Y., Mahamid, J., Pfander, B., Kosinski, J., Beck, M.* (2020). In cell architecture of the nuclear pore complex and snapshots of its turnover. Nature 586, 796-800.
Turoňová, B., Sikora, M., Schürmann, C., Hagen, W.J.H., Welsch, S., Blanc, F.E.C., von Bülow, S., Gecht, M., Bagola, K., Hörner, C., v Zandbergen, G., Landry, J., Doimo de Azevedo, N.T., Mosalaganti, S., Schwarz, A., Covino, R., Mühlebach, M.D., Hummer, G.*, Krijnse Locker, J.*, Beck, M*. (2020). In situ structural analysis of SARS-CoV-2 spike reveals flexibility mediated by three hinges. Science 370, 203-208.
Hampoelz, B., Schwarz, A., Ronchi, P., Bragulat-Teixidor, H., Tischer, C., Gaspar, I., Ephrussi, A., Schwab, Y. and Beck, M.* (2019). Nuclear Pores Assemble from Nucleoporin Condensates During Oogenesis. Cell 179(3), 671-686.
Hampoelz, B., Mackmull, M.-T., Machado, P., Ronchi, P., Bui, K.H., Schieber, N., Santarella-Mellwig, R. Necakov, A., Andres-Pons, A., Philippe, J.M., Lecuit, T., Schwab, Y. and Beck, M.* (2016). Pre-assembled nuclear pores insert into the nuclear envelope during early development. Cell 166(3), 664-678.
Kosinski, J., Mosalaganti, S., von Appen, A., Teimer, R., DiGuilio, L., Wan, W., Bui, H.K., Hagen W.J.H., Briggs, J.A.G., Glavy, J.S., Hurt, E. and Beck, M.* (2016). Molecular architecture of the inner ring scaffold of the human nuclear pore complex. Science 352, 363-5.
von Appen, A., Kosinski, J., Sparks, L., Ori, A., DiGuilio, A.L., Vollmer, B., Mackmull, M.-T., Banterle, N., Parca, L., Kastritis, P., Buczak, K., Mosalaganti, S., Hagen, W., Andres-Pons, A., Lemke, E.A., Bork, P., Antonin, W., Glavy, J.S., Bui, H.K.* and Beck, M.* (2015). In situ structural analysis of the human nuclear pore complex. Nature 526, 140–143.
Bui, H.K., von Appen, A., DiGuilio, A.L., Ori, A., Sparks, L., Mackmull, M.-T., Bock, T., Hagen, W., Andres-Pons, A., Glavy, J.S.* and Beck, M.* (2013). Integrated structural analysis of the human nuclear pore complex scaffold. Cell 155(6), 1233-43.
Ori A, Banterle N, Iskar M, Andrés-Pons A, Escher C, Bui HK, Sparks L, Solis-Mezarino VM, Rinner O, Bork P, Lemke EA, Beck M. 2013. Cell type-specific nuclear pores: A case in point for context-dependent stoichiometry of molecular machines. Molecular Systems Biology 9, 648
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