Dr. Victoria Ingham
Department of Infectious Diseases, Parasitology
Heidelberg University Hospital
Im Neuenheimer Feld 324
69120 Heidelberg, Germany
Phone: +49 6221-56 35236
Fax: +49 6221
E-Mail
FIELDS OF INTEREST
I am interested in how insecticide resistance develops in the malaria mosquito (Anopheles) in endemic settings in response to intense use of insecticide treated bed nets and spraying of insecticide. I am particularly interested in elucidating the molecular mechanisms of resistance, using a variety of -omics; including transcriptomics and whole genome sequencing. I am now expanding my research into how use of insecticide-based chemistries impacts the development and subsequent transmission of the malaria parasite
| 2021 – present | DZIF Junior Group Leader, Universitätsklinikum Heidelberg |
| 2017 – 2020 | MRC Skills Development Fellow, Liverpool School of Tropical Medicine |
| 2018 – 2018 | Visiting Scientist, The Broad Institute |
| 2017 – 2017 | Visiting Scientist, Harvard University |
| 2016 -2017 | Postdoctoral Research Associate, Liverpool School of Tropical Medicine |
| 2015 – 2016 | Research Associate, Liverpool School of Tropical Medicine |
| 2019 – 2020 | Athena Swan Data Lead, Liverpool School of Tropical Medicine |
| 2020 – 2020 | DORA Working Group Member, Liverpool School of Tropical Medicine |
| 2018 – 2020 | ECR Committee Member, Liverpool School of Tropical Medicine |
Integration of whole genome sequencing and transcriptomics reveals a complex picture of the reestablishment of insecticide resistance in the major malaria vector Anopheles coluzzii. V A Ingham et al. PLoS Genetics, 2021, 17(12):e1009970
Capturing the transcription factor interactome in response to sub-lethal insecticide exposure. V A Ingham et al. Current Research in Insect Science 2021, 1:1000018.
Transcriptomic analysis reveals pronounced changes in gene expression due to sublethal pyrethroid exposure and ageing in insecticide resistance Anopheles coluzzii. V A Ingham, F Brown and H Ranson. BMC Genomics 2021, 22:337.
Steroid hormone agonists reduce female fitness in insecticide-resistant Anopheles populations. F Brown, D G Paton, F Catteruccia, H Ranson and V A Ingham. Insect Biochemistry and Molecular Biology, 2020, 121:103372
Effects of insecticide resistance and exposure on Plasmodium development in Anopheles mosquitoes. C Minietti, V A Ingham and H Ranson. Current Opinion in Insect Science, 2020, 39:42-49
A sensory appendage protein protects malaria vectors from pyrethroids. V A Ingham et al. Nature, 2019, 577:376–380
Transcriptomic meta-signatures identified in Anopheles gambiae populations reveal previously undetected insecticide resistance mechanisms. V A Ingham, S Wagstaff and H Ranson. Nature Communications, 2018, 9:5282
The transcription factor Maf-S regulates metabolic resistance to insecticides in the malaria vector Anopheles gambiae. V A Ingham et al. BMC Genomics, 2017, 18:669
The Anopheles gambiae ATP-binding cassette transporter family: phylogenetic analysis and tissue localization provide clues on function and role in insecticide resistance. P. Pignatelli*, V A Ingham* et al. Insect Molecular Biology, 2017, 27:110-122
Dissecting the organ specificity of insecticide resistance candidates in Anopheles gambiae: known and novel candidate genes. V A Ingham et al. BMC Genomics, 2014, 15:1018
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