Dr. Victoria Ingham

Department of Infectious Diseases, Parasitology
Heidelberg University Hospital
Im Neuenheimer Feld 324
69120 Heidelberg, Germany

Phone: +49 6221-56 35236
Fax:      +49 6221


I am interested in how insecticide resistance develops in the malaria mosquito (Anopheles) in endemic settings in response to intense use of insecticide treated bed nets and spraying of insecticide. I am particularly interested in elucidating the molecular mechanisms of resistance, using a variety of -omics; including transcriptomics and whole genome sequencing. I am now expanding my research into how use of insecticide-based chemistries impacts the development and subsequent transmission of the malaria parasite

2021 – present DZIF Junior Group Leader, Universitätsklinikum Heidelberg
2017 – 2020 MRC Skills Development Fellow, Liverpool School of Tropical Medicine
2018 – 2018 Visiting Scientist, The Broad Institute
2017 – 2017 Visiting Scientist, Harvard University
2016 -2017 Postdoctoral Research Associate, Liverpool School of Tropical Medicine
2015 – 2016 Research Associate, Liverpool School of Tropical Medicine

2019 – 2020 Athena Swan Data Lead, Liverpool School of Tropical Medicine
2020 – 2020 DORA Working Group Member, Liverpool School of Tropical Medicine
2018 – 2020 ECR Committee Member, Liverpool School of Tropical Medicine

Integration of whole genome sequencing and transcriptomics reveals a complex picture of the reestablishment of insecticide resistance in the major malaria vector Anopheles coluzzii. V A Ingham et al. PLoS Genetics, 2021, 17(12):e1009970

Capturing the transcription factor interactome in response to sub-lethal insecticide exposure. V A Ingham et al. Current Research in Insect Science 2021, 1:1000018.

Transcriptomic analysis reveals pronounced changes in gene expression due to sublethal pyrethroid exposure and ageing in insecticide resistance Anopheles coluzzii. V A Ingham, F Brown and H Ranson. BMC Genomics 2021, 22:337.

Steroid hormone agonists reduce female fitness in insecticide-resistant Anopheles populations. F Brown, D G Paton, F Catteruccia, H Ranson and V A Ingham. Insect Biochemistry and Molecular Biology, 2020, 121:103372

Effects of insecticide resistance and exposure on Plasmodium development in Anopheles mosquitoes. C Minietti, V A Ingham and H Ranson. Current Opinion in Insect Science, 2020, 39:42-49

A sensory appendage protein protects malaria vectors from pyrethroids. V A Ingham et al. Nature, 2019, 577:376–380

Transcriptomic meta-signatures identified in Anopheles gambiae populations reveal previously undetected insecticide resistance mechanisms. V A Ingham, S Wagstaff and H Ranson. Nature Communications, 2018, 9:5282

The transcription factor Maf-S regulates metabolic resistance to insecticides in the malaria vector Anopheles gambiae. V A Ingham et al. BMC Genomics, 2017, 18:669

The Anopheles gambiae ATP-binding cassette transporter family: phylogenetic analysis and tissue localization provide clues on function and role in insecticide resistance. P. Pignatelli*, V A Ingham* et al. Insect Molecular Biology, 2017, 27:110-122

Dissecting the organ specificity of insecticide resistance candidates in Anopheles gambiae: known and novel candidate genes. V A Ingham et al. BMC Genomics, 2014, 15:1018

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