SFB 1129 plans to obtain an integrative perspective on the mutual interplay of pathogen and host factors determining the outcome of an infection for individual events in systems of different complexity and at high spatial and temporal resolution.

Integration on several levels: scales, complexities, disciplines.

SFB 1129 will…

…directly determine the course of individual pathogens and host countermeasures in culture systems of increasing complexity.

…delineate the influence of physical parameters and extracellular matrix on pathogen success and control.

…comprehensively analyse replication and spread of human pathogens in a quantitative manner at high temporal and spatial resolution and at the level of stochastic events.